Nouryon, formerly AkzoNobel Specialty Chemicals has initiated the third Imagine Chemistry effort looking for open collaboration with startups, scale-ups, and researchers to work with us to tackle some of the biggest challenges facing the chemicals industry. The challenges this year include bio-based surfactants, sensors for demanding environments, nano-particles, chemical innovations that push the frontiers and label-free chemistries. The last challenge, "label-free chemistries" is what prompts my question to the AIChE Discussion site. We have had only one submission so far and I thought this group could provide some valuable insight into the question "What does label-free chemistries mean to you and have you heard of the term? In addition, does anyone think a better term should be used and any suggestions on organizations to reach out to with this challenge. I look forward to your responses.
Label-free quantification is a method in mass spectrometry that aims to determine the relative amount of proteins in two or more biological samples. Unlike other methods for protein quantification, label-free quantification does not use a stable isotope containing compound to chemically bind to and thus label the protein.
Interestingly, I recall a story that David Wesson, founder of Wesson Oil, kept all his processing parameters unknown to workers and casual observers by creating his own standards for processing parameters and measurements such as "degrees Wesson" rather than known parameters like Farienheight or Celsius. Could it be a reference to concealing chemistry for proprietary reasons within the confines of a production operation?
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